This model compares the transplantation of skin allograft and autograft between two animals to evaluate novel immunosuppressive treatments.

A simple and fast in vivo model to evaluate the efficacy of your drug.


  • Species: Cynomolgus macaque (Macaca fascicularis)
  • Validation of the model :
    • Clinical and histopathological validation
    • Validated with reference immunosuppressive drug (Thymoglobulin)

Type of test item

  • Immunotherapies
  • Immunomodulators

Efficacy read-outs

  • Scoring of skin graft, skin inflammation and other clinical signs lesions observed as in human
  • Clinical pathology
  • Immunomonitoring
  • Skin biopsies, tissue collection
  • Histopathology
  • Immunohistochemistry
  • On-demand and customized readouts